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Medchemexpress LLC Fumagilin-105 | 2410081-58-0 | >97.34% | 784.98 | 1 MG

Supplier: Medchemexpress LLC HY1617421MG
Fumagilin-105 is an autophagy-targeting chimera (AUTOTAC) that degrades MetAP2 via p62-mediated macroautophagy in a ubiquitination-independent manner. It can inhibit the migration of tumor cells and induce programmed cell death, demonstrating anti-tumor activity.
- Autophagy-targeting chimera (AUTOTAC)
- Degrades MetAP2 via p62-mediated macroautophagy
- Utilizes a ubiquitination-independent degradation mechanism
- Inhibits the migration of tumor cells
- Induces programmed cell death
- Possesses anti-tumor activity
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