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Selleck Chemical LLC Fumonisin B1
Supplier: Selleck Chemical LLC S78661MG
Fumonisin B1 is a mycotoxin produced by Fusarium moniliforme Sheldon and a potent inhibitor of sphingosine N-acyltransferase (ceramide synthase) an enzyme vital for the de novo synthesis of sphingolipids It exhibits an IC50 of 0 1 M for N-acyltransferase (ceramide synthase) in rat liver microsomes and also reduces the conversion of [3H]sphingosine to [3H]ceramide in intact hepatocytes
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