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Fumonisin B2, 96+%

Catalog No. AC328260010
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Catalog No. AC328260010 Supplier Thermo Scientific Chemicals Supplier No. 328260010
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Description

Fumonisin B2, CAS # 116355-84-1, is a diester of tricarballylic acid and is isolated from Fusarium. | CAS: 116355-84-1 | C34H59NO14·3H2O | 759.9 g/mol

This Thermo Scientific Chemicals brand product was originally part of the Acros Organics product portfolio. Some documentation and label information may refer to the legacy brand. The original Acros Organics product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

General Description

  • Fumonisin B2 is a fumonisin mycotoxin produced by the fungus Fusarium
  • Fumonisin B2 is a structural analog of fumonisin B1 but it is more cytotoxic than B1 and can inhibit sphinganine-N-acetyltransferase (ceramide synthase)

Applications

  • In vitro and in vivo studies have shown Fumonisin B2 can induce apoptosis
  • It can inhibit de novo sphingolipid biosynthesis
  • It is also considered an Aspergillus metabolite
  • It shows cytotoxicity against a panel of seven rat hepatoma cell lines, and MDCK cell line
  • It induces hepatocyte nodule formation, a marker of cancer initiation, in rats
TRUSTED_SUSTAINABILITY

Chemical Identifiers

CAS 116355-84-1
Molecular Formula C34H59NO14·3H2O
Molecular Weight (g/mol) 759.9
InChI Key UXDPXZQHTDAXOZ-FWPUDPCBSA-N
Synonym fumonisin b2, 2r,2'r-1,2,3-propanetricarboxylic acid 1,1'-1s,2r-1-2s,9r,11s,12s-12-amino-4,9,11-trihydroxy-2-methyltridecyl-2-1r-1-methylpentyl-1,2-ethanediyl ester, 2s-2-2-5r,6r,7s,9s,16r,18s,19s-19-amino-6-3r-3,4-dicarboxybutanoyl oxy-16,18-dihydroxy-5,9-dimethylicosan-7-yl oxy-2-oxoethyl butanedioic acid
PubChem CID 71317007
IUPAC Name (2S)-2-[2-[(5R,6R,7S,9S,16R,18S,19S)-19-amino-6-[(3R)-3,4-dicarboxybutanoyl]oxy-16,18-dihydroxy-5,9-dimethylicosan-7-yl]oxy-2-oxoethyl]butanedioic acid
SMILES CCCCC(C)C(C(CC(C)CCCCCCC(CC(C(C)N)O)O)OC(=O)CC(CC(=O)O)C(=O)O)OC(=O)CC(CC(=O)O)C(=O)O

Specifications

Assay Percent Range 96+%
Quantity 1 mg
Solubility Information Solubility in water: .. Other solubilities: soluble in methanol
Formula Weight 759.9
Percent Purity 96+%
Chemical Name or Material Fumonisin B2

Safety and Handling

Hazard Category GHS Signal Word: Danger
SDS

RUO – Research Use Only

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