Fura 2-AM, MP Biomedicals™

Description

Permeates cell membranes. Fura 2-AM, MP Biomedicals is a fluorescent probe for Ca2+ and is used to determine cystolic Ca2+. Fura 2-AM is the acetoxymethyl ester of Fura 2. It is metabolized in vivo to the active ligand Fura 2.

• Able to permeate cell membranes and load Fura 2 into cells
• Inside cells, Fura 2-AM is rapidly hydrolyzed by cytoplasmic esterases

Specifications

Chemical Identifiers

• CAS: 108964-32-5
• Molecular Formula: C44H47N3O24
• Molecular Weight (g/mol): 1001.857
• InChI Key: VPSRLGDRGCKUTK-UHFFFAOYSA-N
• Synonym: fura 2-am, fura-2 pentakis acetoxymethyl ester, bis acetoxymethyl 2,2'-2-5-acetoxymethoxy carbonyl oxazol-2-yl-5-2-2-bis 2-acetoxymethoxy-2-oxoethyl amino-5-methylphenoxy ethoxy benzofuran-6-yl azanediyl diacetate, fura-2 am, fura-2-acetoxymethyl ester, 1-2-5-carboxyoxazol-2-yl-6-aminobenzofuran-5-oxy-2-2′-amino-5′-methylphenoxy-ethane-n,n,n′n′-tetraacetic acid pentaacetoxymethyl ester, 1-6-amino-2-5-carboxy-2-oxazolyl-5-benzofuranyloxy-2-2-amino-5-methylphenoxy ethane-n,n,n',n'-tetraacetic acid, pentaacetoxymethyl ester, fura-2/am, fura-2 acetoxymethyl ester, fura 2-am hplc
• PubChem CID: 3364574
• IUPAC Name: acetyloxymethyl 2-[6-[bis[2-(acetyloxymethoxy)-2-oxoethyl]amino]-5-[2-[2-[bis[2-(acetyloxymethoxy)-2-oxoethyl]amino]-5-methylphenoxy]ethoxy]-1-benzofuran-2-yl]-1,3-oxazole-5-carboxylate
• SMILES: CC1=CC(=C(C=C1)N(CC(=O)OCOC(=O)C)CC(=O)OCOC(=O)C)OCCOC2=C(C=C3C(=C2)C=C(O3)C4=NC=C(O4)C(=O)OCOC(=O)C)N(CC(=O)OCOC(=O)C)CC(=O)OCOC(=O)C

• Quantity: 500 μg
• Solubility Information: The acetoxymethyl ester of the chelator is soluble in dimethylsulfoxide (10mg/mL) and in nonpolar solvents such as chloroform, acetone and benzene. It is insoluble in water or methanol.
• Formula Weight: 1001.9
• Physical Form: Solid

Safety and Handling

Recommended Storage

−20°C