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Cayman Chemical FuramIdInhydrochlorIde 10mg
Supplier: Cayman Chemical 1912110 MG
A cell-permeable inhibitor with selectivity for PRMT1 (IC50 = 9.4 μM) over PRMT5, PRMT6, and PRMT4/CARM1 (IC50s = 166, 283, and >400 μM, respectively); inhibits Aly protein methylation in HEK293T cells and growth of several leukemia cell lines when used at a concentration of 20 μM; inhibits Tdp1 activity on single- and double-stranded DNA with concentrations in the low micromolar range; inhibits T. brucei (IC50 values of 1.5 to 37 nM across various strains); inhibits the T. brucei P2 aminopurine transporter (Ki = 1.2 μM); binds to AT-rich DNA sequences
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