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Medchemexpress LLC Furosemide-d5 | 1189482-35-6 | 99.9% | 1 MG
Supplier: Medchemexpress LLC HYB0135S1MG
Furosemide-d5 is the deuterium labeled Furosemide. Furosemide is a potent and orally active inhibitor of Na+/K+/2Cl- (NKCC) cotransporter, specifically NKCC1 and NKCC2. It also acts as a GABAA receptors antagonist, showing 100-fold selectivity for α6-containing receptors over α1-containing receptors. Furosemide is a loop diuretic used in the study of congestive heart failure, hypertension, and edema. Deuterium substitution in drug molecules is explored for its potential impact on pharmacokinetic and metabolic profiles.
- Can be used as a tracer
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS
- Potent and orally active inhibitor of Na+/K+/2Cl- (NKCC) cotransporter
- Acts as a GABAA receptors antagonist
- Used in the study of congestive heart failure, hypertension, and edema
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