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Apexbio Technology LLC G-36 1392487-51-2 10mg

Supplier: Apexbio Technology LLC B570710
G-36 (CAS 1392487-51-2) is a non-steroidal antagonist targeting the G protein-coupled estrogen receptor (GPER/GPR30) It is designed to selectively inhibit GPER-mediated signaling thereby regulating estrogen-induced cellular pathways G-36 exerts its biological activity primarily through selective blockade of GPER without affecting estrogen receptor alpha (ER ) In cell-based assays G-36 demonstrates inhibitory activity on estrogen-mediated calcium mobilization with an IC50 value of approximately 112 nM Based on these pharmacological properties G-36 holds research potential in investigating estrogen-associated signaling particularly in cancer biology and related therapeutic studies
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