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Medchemexpress LLC G150 | 2369751-30-2 | 99.2% | 50 MG
SDP

Supplier:  Medchemexpress LLC HY12858350MG

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G150 is a highly selective human cyclic GMP-AMP synthase (h-cGAS) inhibitor with an IC50 of 10.2 nM. It represses dsDNA-triggered interferon expression and can be used for research on inflammatory conditions. For research use only.

  • Highly selective human cyclic GMP-AMP synthase (h-cGAS) inhibitor
  • Represses dsDNA-triggered interferon expression
  • Used for inflammatory research
  • Effective in inhibiting IFNB1 and CXCL10 expression in human THP1 cells and primary human macrophages
  • Inhibits dsDNA sensing in THP1 cells and primary human macrophages
  • Affects the NF-κB pathway activation in THP1-Dual cells

Catalog No. 50-003-42525


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