Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More
Learn More
Medchemexpress LLC GA-017 | 2351906-74-4 | 99.0% | 343.38 | 1 ML
Supplier: Medchemexpress LLC HY14708210MM/1ML
GA-017 is a potent and selective inhibitor of large tumor suppressor kinase 1/2 (LATS1/2), with IC50 values of 4.10 nM and 3.92 nM respectively. It acts as an activator of cell proliferation, promoting YAP/TAZ activation and nuclear translocation. This compound supports cell growth under 3D culture conditions and enhances the ex vivo formation of mouse intestinal organoids, and also suppresses cell death of HUVECs.
- Potent and selective LATS1/2 inhibitor
- Activator of cell proliferation
- Promotes YAP/TAZ activation and nuclear translocation
- Supports cell growth under 3D culture conditions
- Enhances ex vivo formation of mouse intestinal organoids
- Suppresses cell death of HUVECs and promotes cell growth
- Facilitates SKOV3 cell growth with an EC50 of 3.51 ± 0.26 μM
- Competitively inhibits LATS1 and 2 against ATP
Product Title
By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.
Spot an opportunity for improvement?