Gabapentin, 98%, Thermo Scientific Chemicals

Description

Gabapentin, CAS # 60142-96-3, is a synthetic analogue of the neurotransmitter gamma-aminobutyric acid with anticonvulsant and analgesic activities.

This Thermo Scientific Chemicals brand product was originally part of the Acros Organics product portfolio. Some documentation and label information may refer to the legacy brand. The original Acros Organics product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

General Description

• Gabapentin is a water-soluble GABA analog with anticonvulsant and analgesic activities

• The exact mechanism of action is unknown but it has been described that this compound inhibits excitatory neuron activity by interacting with voltage-gated calcium channels in cortical neurons

Application

• Gabapentin has been used as the α2δ-ligand to examine whether the allyl isothiocyanate (AITC) sensitized thermal aversion assay might be useful as a screening method for the identification of presumptive analgesics

Specifications

Chemical Identifiers

• CAS: 60142-96-3
• Molecular Formula: C₉H₁₇NO₂
• Molecular Weight (g/mol): 171.24
• InChI Key: UGJMXCAKCUNAIE-UHFFFAOYSA-N
• Synonym: gabapentin, neurontin, gabapentine, 1-aminomethyl cyclohexaneacetic acid, 2-1-aminomethyl cyclohexyl acetic acid, aclonium, gabapentinum, gabapetin, gabapentino, fanatrex
• PubChem CID: 3446
• ChEBI: CHEBI:42797
• IUPAC Name: 2-[1-(aminomethyl)cyclohexyl]acetic acid
• SMILES: C1CCC(CC1)(CC(=O)O)CN

• Melting Point: 166.0°C
• Infrared Spectrum: Authentic
• Linear Formula: COOHCH₂C₆H₁₀CH₂NH₂
• Formula Weight: 171.24
• Quantity: 1 g
• Chemical Name or Material: Gabapentin

Safety and Handling

Hazard Category	GHS Signal Word: Danger
Hazard Statement	GHS H Statement Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation. May damage the unborn child.
Precautionary Statement	GHS P Statement IF ON SKIN: Wash with plenty of soap and water. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses,if present and easy to do. Continue rinsing. IF INHALED: Remove to fresh air and kee
EINECSNumber	262-076-3

SDS

RUO – Research Use Only