Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More
Learn More
Medchemexpress LLC Gala | 107658-43-5 | 99.04% | 3032.36 | 10 MG
Supplier: Medchemexpress LLC HYP542310MG
GALA is a pH-responsive amphipathic peptide composed of 30 amino acids, functioning as a lung endothelium-targeting ligand. It transitions from a random coil to an α-helix in an acidic environment (pH 5.0), leading to endosomal membrane destabilization and fusion. GALA-modified liposomes cross lung endothelial cells via clathrin-dependent endocytosis and transcytosis, accumulating specifically in the lungs after intravenous injection.
- Enhances cytosolic release of cargos from exosomes, plasmids, and liposomes
- Improves gene transfection efficiency and drives gene knockdown of functional macromolecules (e.g., siRNA) in alveolar epithelial cells
- Vital tool for studying lung cancer metastasis and lung-targeted drug delivery systems
- No significant cytotoxicity at effective concentrations
Product Title
By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.
Spot an opportunity for improvement?