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Cayman Chemical GalnontrIfluoROCTAte salt 10mg
Supplier: Cayman Chemical 2992510 MG
A galanin receptor agonist (KD = 2.9 µM in Bowes cells expressing GAL1 receptors); inhibits forskolin-induced adenylate cyclase activity in rat hippocampal membranes (EC50 = 10 µM); reduces the maximal seizure score and increases the latency to first seizure in a mouse model of PTZ-induced seizures at 2 mg/kg; reduces cocaine-induced motor activity and frontal cortex, but not nucleus accumbens, dopamine overflow, as well as blocks cocaine-primed reinstatement of cocaine-seeking behavior in rats; reduces food intake in rats and mice from 1.5-5 mg/kg
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