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Medchemexpress LLC Gamma-glutamylcysteine TFA | 283159-88-6 | 95.2% | 364.30 | 10 MG
Supplier: Medchemexpress LLC HY113402A10MG
Gamma-glutamylcysteine TFA is an orally active, blood-brain barrier permeable dipeptide involved in regulating macrophage polarization, inducing glutathione synthesis, and improving metabolic dysfunction. It is relevant for research in various diseases.
- Orally active and blood-brain barrier permeable dipeptide.
- Activates AMPK, SIRT1, IL-4/STAT6, AC/cAMP/PI3K, IGF-1R/IRS1/PI3K, and Nrf2 signaling pathways.
- Inhibits NF-κB, JAK1/STAT1/3, MAPKs, and PI3K/Akt signaling pathways.
- Regulates macrophage polarization and modulates CD36 and GLUT4 trafficking.
- Induces glutathione synthesis, improves metabolic dysfunction, and ameliorates glucose homeostasis.
- Reduces lipid deposition, inhibits apoptosis, stabilizes mitochondria, and suppresses ferroptosis.
- Relevant for research in inflammatory bowel disease, type 2 diabetes, Alzheimer's disease, and alcoholic liver disease.
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