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Medchemexpress LLC Gamma-Mangostin | 31271-07-5 | 396.43 | 1 ML
SDP

Supplier:  Medchemexpress LLC HYN195710MM/1ML

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Gamma-Mangostin is a novel competitive 5-hydroxytryptamine 2A (5-HT2A) receptor antagonist and a potent cyclooxygenase-2 (COX-2) inhibitor, as well as a transthyroxin protein (TTR) profibrosis inhibitor. It functions by binding to the thyroxine (T4)-binding sites, which stabilizes the TTR tetramer. This compound exhibits anti-inflammatory, antibacterial, antioxidant, and anticancer activities, making it suitable for studies related to metabolic disorders such as diabetes.

  • Inhibits [3H] spiperone binding to cultured rat aortic myocytes (IC50=3.5 nM).
  • Reduces the perfusion pressure response of rat coronary artery to 5-HT2A (IC50=0.32 μM).
  • Possesses anti-inflammatory, antibacterial, antioxidant, and anticancer activities.
  • Can be utilized in the study of metabolic disorders such as diabetes.

Catalog No. 50-004-16179


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