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Sigma Aldrich Gamma-[(Propargyl)-Imido]-Atp Sodium Salt

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80-851-21MG 1 mg
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Description

MilliporeSigma Sigma Organics products encompass a wide range of quality reagents, solvents, catalysts, and building blocks for organic synthesis. From benchtop discovery to process development and scale-up, Sigma Organics solutions are built to meet the needs of synthetic chemists.

Lee, et al,. reported a non-radioactive version of in vitro phosphorylation where +a-[(Propargyl)-imido]-ATP (compound 1) was successfully used instead of +a-32P-modified ATP to phosphorylate GST-tagged recombinant p27kip1 with protein kinase cdk2. The phosphorylated, alkyne-modified protein substrate can be labeled with azides of biotin or fluorescent dyes using Cu(I)-catalyzed click chemistry.The purchase of this product for use in applications relating to copper catalyzed azide-alkyne cycloaddition chemistry (Click Chemistry) includes a limited, nontransferable license to intellectual property owned by The Scripps Research Institute to use this product solely for internal non-commercial research activities and specifically excludes clinical, therapeutic, or diagnostic use in humans or animals and manufacturing purposes. Information regarding a license for commercial use in Click Chemistry may be obtained directly from The Scripps Research Institute, 10550 N. Torrey Pines Rd., La Jolla, CA 92037, or by contacting 858-784-8140 or click@scripps.edu.

Specifications

CAS 207386-83-2
Molecular Formula C16H28N9O12P3 -+ xNa+
Linear Formula C16H28N9O12P3 -+ xNa+
Quantity 1 mg
Synonym gamma-[(6-Azidohexyl)-imido]-adenosine-5'-triphosphate sodium salt
Molecular Weight (g/mol) 631.37 (free acid basis) g/mol
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