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Invivogen Ganciclovir (GCV), 82410-32-0, MFCD00870588, 250mg

Supplier: Invivogen SUDGCV
Molecular Formula C9H13N5O4, Molecular weight 255.2, Ganciclovir (GCV) is a guanosine analog used as a prodrug to obtain a suicide effect in cells transfected with the herpes virus thymidine kinase gene (HSV-tk). HSVTK phosphorylates GCV to GCV-monophosphate which is further converted to GCV-diphosphate and GCV-triphosphate by host kinases. GCV-triphosphate causes premature DNA chain termination and apoptosis.
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