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AdipoGen Ganglioside GQ1b . tetrasodium salt (500 µg)
Supplier: AdipoGen AGCN29007C500
Chemical. CAS: 68652-37-9. Formula: C106H178N6O55 . 4Na. MW: 2416.6 . 92.0 (calculated on sphingosine C18:1 and stearic acid). Isolated from bovine brain. Gangliosides are acidic glycosphingolipids that form lipid rafts in the outer leaflet of the cell plasma membrane, especially in neuronal cells in the central nervous system. They participate in cellular proliferation, differentiation, adhesion, signal transduction, cell-to-cell interactions, tumorigenesis and metastasis. The accumulation of gangliosides has been linked to several diseases. Ganglioside GQ1b specifically promotes neural differentiation of human neuroblastoma cells. Anti-GQ1b antibodies are present in serum from Miller-Fisher syndrome patients.
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