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AdipoGen Ganglioside GT1b . trisodium salt (1 mg)
Supplier: AdipoGen AGCN29006M001
Chemical. CAS: 59247-13-1. Formula: C95H162N5O47 . 3Na. MW: 2126.3 . 69.0 (calculated on sphingosine C18:1 and stearic acid). Isolated from bovine brain. Gangliosides are acidic glycosphingolipids that form lipid rafts in the outer leaflet of the cell plasma membrane, especially in neuronal cells in the central nervous system. They participate in cellular proliferation, differentiation, adhesion, signal transduction, cell-to-cell interactions, tumorigenesis and metastasis. The accumulation of gangliosides has been linked to several diseases. Ganglioside GT1b binds botulinum and tetanus neurotoxins and it prevents neurotoxicity of glutamate on neuronal cells.
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