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Medchemexpress LLC Gap 27 | 198284-64-9 | 99.9% | 1304.53 | 5 MG
SDP

Catalog No. 5000426395
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Gap 27 is a synthetic connexin43 mimetic peptide and a gap junction inhibitor. It has conserved sequence homology to a portion of the second extracellular loop leading into the fourth transmembrane connexin segment.

  • Significantly reduces the number and activity of TRAP-positive mononuclear and multinucleated rat osteoclasts cultured on bovine bone slices
  • Diminishes the resorbed area
  • Inhibits acetylcholine-induced, endothelium-dependent hyperpolarizations in the guinea-pig isolated internal carotid artery
  • Inhibits relaxation in the thoracic aorta and superior mesenteric artery
  • Attenuates the endothelium-dependent component of ATP-induced relaxation in the thoracic aorta

Catalog No. 50-004-26395 Supplier Medchemexpress LLC Supplier No. HYP01395MG
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Gap 27 is a synthetic connexin43 mimetic peptide and a gap junction inhibitor. It has conserved sequence homology to a portion of the second extracellular loop leading into the fourth transmembrane connexin segment.

  • Significantly reduces the number and activity of TRAP-positive mononuclear and multinucleated rat osteoclasts cultured on bovine bone slices
  • Diminishes the resorbed area
  • Inhibits acetylcholine-induced, endothelium-dependent hyperpolarizations in the guinea-pig isolated internal carotid artery
  • Inhibits relaxation in the thoracic aorta and superior mesenteric artery
  • Attenuates the endothelium-dependent component of ATP-induced relaxation in the thoracic aorta

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