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Medchemexpress LLC Garcinone D | 107390-08-9 | 25 MG

Supplier: Medchemexpress LLC 25MGHYN6953
Garcinone D is an activator of the STAT3/Cyclin D1 and Nrf2/HO-1 pathways and an inhibitor of CDK2/CyclinE1. It promotes neural stem cell proliferation by activating STAT3 phosphorylation and Cyclin D1 expression, and by enhancing the Nrf2/HO-1 signaling pathway. Additionally, it blocks the tumor cell cycle by inhibiting CDK2/CyclinE1.
- Activates STAT3/Cyclin D1 and Nrf2/HO-1 pathways
- Inhibits CDK2/CyclinE1 (IC50 is 28.23 μM)
- Promotes neural stem cell proliferation
- Blocks tumor cell cycle
- Can inhibit prostate and breast cancer
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