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Cayman Chemical GBR 12783hydrochlorIde 10mg

Supplier: Cayman Chemical 3566210 MG
A dopamine uptake inhibitor (IC50 = 13 nM in rat striatal synaptosomes); selective for inhibition of dopamine uptake over norepinephrine or 5-HT uptake (IC50s = 230 and 1,100 nM in rat hypothalamic and striatal synaptosomes, respectively); improves learning and memory in the passive avoidance test in rats at 10 mg/kg, i.p., an effect that can be blocked by scopolamine; increases locomotor activity, reduces pentobarbital-induced sleep duration, and decreases immobility time in the forced swim test, in mice; inhibits haloperidol-induced catalepsy in rats at 10 mg/kg
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