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Medchemexpress LLC Gcn2-in-6 (compound 6d) | 2183470-09-7 | 98.9% | C19H12Cl2F2N4O3S | 10MG
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Supplier:  Medchemexpress LLC HY13024010MG

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GCN2-IN-6 is a small-molecule inhibitor of the eIF2α kinase GCN2 used as a research tool to probe the integrated stress response and related signaling pathways. It has been characterized in enzymatic and cellular assays and is provided for laboratory research in solid and DMSO solution formats.

  • Potent GCN2 inhibitor with enzymatic IC50 ~1.8 nM and cellular IC50 ~9.3 nM.
  • Also shows activity against PERK in enzymatic and cellular assays.
  • High nominal purity (~98.9% as listed on product page).
  • Molecular formula C19H12Cl2F2N4O3S; molecular weight 485.29.
  • Available as mg-scale solid and 10 mM DMSO solutions for convenient use.
  • CAS 2183470-09-7 for unambiguous chemical identification.

Catalog No. 50-002-60012


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