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Medchemexpress LLC Gdp366 | 501698-03-9 | 375.45 | 10 MG
Supplier: Medchemexpress LLC HYU0017710MG
GDP366 is a dual inhibitor of survivin and Op18 that induces cell growth inhibition, cellular senescence, and mitotic catastrophe in human cancer cells.
- Potently and selectively inhibits survivin and Op18 expression.
- Decreases survivin and Op18 mRNA and protein levels.
- Significantly inhibits tumor cell growth in vitro and in vivo.
- Induces polyploidy and increases chromosomal instability in cancer cells.
- Promotes cellular senescence by inhibiting telomerase activity.
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