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Cayman Chemical GefItInIb-based PROTAC 3 25mg
Supplier: Cayman Chemical 2859725 MG
A PROTAC comprised of gefitinib linked to VHL ligand 1; induces degradation of EGFR containing the activating mutation L858R or an exon 19 deletion (DC50s = 22.3 and 11.7 nM, respectively) but does not induce degradation of wild-type EGFR at ≤10 μM in cell-based assays
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