Medchemexpress LLC Gefitinib hydrochloride | 184475-55-6 | 99.8% | 500 MG

Supplier:  Medchemexpress LLC HY50895A500MG

Gefitinib hydrochloride (ZD1839 hydrochloride) is a potent, selective, and orally active inhibitor of EGFR tyrosine kinase, with an IC50 of 33 nM. It specifically inhibits EGF-stimulated tumor cell growth with an IC50 of 54 nM and blocks EGF-stimulated EGFR autophosphorylation in tumor cells. Additionally, Gefitinib hydrochloride has been shown to induce autophagy and possesses antitumour activity.

• Potent, selective, and orally active EGFR tyrosine kinase inhibitor.
• Inhibits EGF-stimulated tumor cell growth.
• Blocks EGF-stimulated EGFR autophosphorylation in tumor cells.
• Induces autophagy.
• Demonstrates antitumour activity.

Catalog No. 50-003-57704