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Medchemexpress LLC Gefitinib hydrochloride | 184475-55-6 | 99.9% | C22H25Cl2FN4O3 | 100 MG
Supplier: Medchemexpress LLC HY50895A100MG
Gefitinib hydrochloride (ZD1839 hydrochloride) is a potent, selective, and orally active EGFR tyrosine kinase inhibitor with an IC50 of 33 nM. It selectively inhibits EGF-stimulated tumor cell growth (IC50 of 54 nM) and blocks EGF-stimulated EGFR autophosphorylation in tumor cells. Gefitinib hydrochloride also induces autophagy and has antitumour activity.
- Potent, selective, and orally active EGFR tyrosine kinase inhibitor
- Selectively inhibits EGF-stimulated tumor cell growth
- Blocks EGF-stimulated EGFR autophosphorylation
- Induces autophagy
- Has antitumour activity
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