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Medchemexpress LLC Gefitinib hydrochloride | 184475-55-6 | MFCD00952718 | 99.8% | C22H25Cl2FN4O3 | 1 G
Supplier: Medchemexpress LLC HY50895A1G
Gefitinib hydrochloride is a potent, selective, and orally active EGFR tyrosine kinase inhibitor, intended for research use only. It selectively inhibits EGF-stimulated tumor cell growth and blocks EGFR autophosphorylation in tumor cells. It also induces autophagy and exhibits antitumour activity.
- Potent and selective EGFR tyrosine kinase inhibitor.
- IC50 of 33 nM against EGFR.
- Selectively inhibits EGF-stimulated tumor cell growth with an IC50 of 54 nM.
- Blocks EGF-stimulated EGFR autophosphorylation in tumor cells.
- Induces autophagy.
- Exhibits antitumour activity.
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