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Cayman Chemical GemcItabIn ElaIdate 10mg
Supplier: Cayman Chemical 2830310 MG
A prodrug form of gemcitabine; inhibits growth of gemcitabine-sensitive L1210/L5, BCLO, and A2780 cells (IC50s = 0.0033, 0.0042, and 0.0025 µM, respectively) but not cytarabine-resistant L4A6 and Bara-C cells or gemcitabine-resistant AG6000 cells; reduces tumor growth in EKVX non-small cell lung cancer and MHMX sarcoma mouse xenograft models at 40 mg/kg every three days
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