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AdipoGen Genipin, 6902-77-8, MFCD00888600, 100 mg
Supplier: AdipoGen AGCN20481M100
MF: C11H14O5, MW: 226.2, ≥98%, Appearance: White to off-white solid. Cell permeable inhibitor of uncoupling protein 2. Increases glucose-stimulated insulin secretion, mitochondrial membrane potential and ATP levels in pancreatic island cells. Anticancer, antimetastatic and anti-angiogenic agent. Increases Bax/Bcl-2 ratio and induces PARP cleavage and caspase-3- and caspase-9-mediated apoptosis in non-small cell lung cancer (NSCLC) cells. Sensitizes multidrug-resistant cancer cells to cytotoxic agents through UCP2 inhibition. Suppresses the tumor promoting function of UCP2 in a cellular model of Warburg effect.
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