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Medchemexpress LLC Geniposidic acid | 27741-01-1 | 98.9% | 374.34 | 1 ML
Supplier: Medchemexpress LLC HYN001010MM/1ML
Geniposidic acid is an orally active FXR modulator and SIRT6 activator. It binds to specific sites on the FXR ligand-binding domain, driving nuclear translocation, coactivator recruitment, and transcription of downstream genes related to bile acid and cholesterol metabolism. It also improves metabolic dysfunction-related fatty liver disease by activating the SIRT6 signaling pathway.
- Inhibits inflammation.
- Modulates gut microbiota to alleviate colitis.
- Can be used in research on drug-induced liver injury.
- Applicable for inflammatory bowel disease research.
- Useful for metabolic dysfunction-related fatty liver disease studies.
- Suitable for research on metabolic dysfunction-related steatohepatitis.
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