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AdipoGen Gentamicin sulfate USP Grade
Supplier: AdipoGen AGCN20066G005
Chemical. CAS 1405-41-0. Formula C21H43N5O7 . H2SO4 unspecified. MW 575.6. Isolated from Micromonospora sp. Aminoglycoside antibiotic. Protein synthesis inhibitor. Causes codon misreading by binding to the 30S ribosomal subunit, blocking the translocation of peptidyl-tRNA from the acceptor site to the donor site. Antibacterial against Gram-negative aerobic bacteria, Gram-positive bacteria and mycoplasmas. Used as a selection agent gentamicin-resistance gene in molecular biology applications. Broad-spectrum cell culture antibiotic that is nontoxic to viruses and mammalian cells at antibacterial and antimycoplasmal concentrations. Due to its extended stability and slow development of bacterial resistance, it is a useful antibiotic in long-term virus und tissue culture studies. Bactericidal effects are exerted by the binding to the outer membrane, causing disruption of the membrane.
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