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Apexbio Technology LLC Gentamycin Sulfate(Synonyms: Garamycin, Gentamicin sulfate, Gentamycin sulphate, Garamycin sulfate, Gentacin), 10mM (in 1mL H2O), CAS: 1405-41-0.
Supplier: Apexbio Technology LLC A25145.1
Gentamycin sulfate (CAS 1405-41-0) is an aminoglycoside antibiotic commonly utilized in biomedical research for its bactericidal activity against a broad spectrum of bacterial pathogens particularly Gram-negative aerobes Its mechanism involves irreversible binding to the bacterial 30S ribosomal subunit specifically interacting with 16S rRNA nucleotides near nucleotide 1400 and ribosomal protein S12 This binding disrupts accurate decoding of mRNA resulting in incorporation of incorrect amino acids into nascent peptides and the formation of defective or toxic proteins Gentamycin sulfate serves as a valuable tool in research exploring bacterial protein synthesis ribosome function antibiotic resistance and microbial pathogenicity
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