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Cayman Chemical GGTI 298 trifluoroacetate sa
Supplier: Cayman Chemical 16176500 UG
A CAAX peptidomimetic that selectively inhibits geranylgeranyltransferase I; arrests human tumor cells (IC50 = 10 µM for A549 cells) in G0/G1 and induces apoptosis by inhibiting proteasome activity and up-regulating the expression of the cyclin-dependent kinase inhibitor p21
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