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Medchemexpress LLC Gigantol isomer-1 | 67884-30-4 | 5 MG
Supplier: Medchemexpress LLC HYN25235MG
Gigantol isomer-1 is a bibenzyl compound derived from Dendrobium nobile. It demonstrates promising therapeutic potential against cancer cells and acts as a novel inhibitor of the Wnt/β-catenin pathway.
- Derived from the plant Dendrobium nobile.
- Exhibits promising therapeutic potential against cancer cells.
- Functions as a novel inhibitor of the Wnt/β-catenin pathway.
- Decreases levels of phosphorylated LRP6 and cytosolic β-catenin in HEK293 cells.
- Reduces phosphorylated LRP6 levels in breast cancer MDA-MB-231 and MDA-MB-468 cells.
- Significantly inhibits proliferation and induces apoptosis in HepG2 cells.
- Demonstrated antinociceptive effects by increasing hot-plate latency in mice.
- Exhibits anti-inflammatory effects by decreasing carrageenan-induced inflammation in rats.
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