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Cayman Chemical GInkgolIde A 10mg
Supplier: Cayman Chemical 2497010 MG
A terpenoid lactone with diverse biological activities; inhibits platelet activating factor-dependent aggregation of human platelets (IC50 = 15.8 μg/ml); inhibits GABA-induced currents in Xenopus oocytes expressing human α1β2γ2L GABAA receptors (IC50 = 12 μM); reduces the proliferation rate of OVCA429 ovarian cancer cells by 40% at 100 μM; increases the time spent in the open arms of the elevated plus maze by 3-fold without altering activity level in mice at 1-2 mg/kg; reduces hexobarbital-induced sleeping time in mice by 44% at 10 mg/kg; increases CYP1A2 and CYP2E1 activity by 1.82- and 1.27-fold, respectively, in rats at 30 mg/kg per day
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