Medchemexpress LLC Ginsenoside Rh2 | 78214-33-2 | MFCD00800712 | 622.87 | 50 MG

Supplier:  Medchemexpress LLC HYN060550MG

Ginsenoside Rh2 induces the activation of caspase-8 and caspase-9. It induces cancer cell apoptosis in a multi-path manner, making it a promising candidate for anti-tumor drug development. Ginsenoside Rh2 triggers p53-dependent Fas expression, leading to caspase-8 activation, and also initiates a p53-independent caspase-9-mediated intrinsic pathway to cause cancer cell death.

• Induces activation of caspase-8 and caspase-9.
• Induces cancer cell apoptosis through multiple pathways.
• Triggers p53-dependent Fas expression.
• Activates p53-independent caspase-9-mediated intrinsic pathway.
• Demonstrates cytotoxic activity against various human cancer cell lines (HeLa, SK-HEP-1, SW480, PC-3, A549, B16, B16-F10, DU-145, HCT-116, HL-60, HepG2, Huh-7, Jurkat, K562, KG-1, Kasumi 1, LNCaP, MCF7, MDA-MB-231, REH, THP-1, U-937).
• Enhances antitumor immunological response in a melanoma mice model.

Catalog No. 50-003-88744