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Genscript Corporation GITR/TNFRSF18Biotin His A
Supplier: Genscript Corporation Z04474500
GITR (glucocorticoid-induced tumor necrosis factor receptor) also known as AITR and TNFRSF18 is a 40 kDa transmembrane glycoprotein that functions in immune regulation GIRT is a receptor for TNFSF18 Seems to be involved in interactions between activated T-lymphocytes and endothelial cells and in the regulation of T-cell receptor-mediated cell death Mediated NF-kappa-B activation via the TRAF2/NIK pathway
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