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Medchemexpress LLC Givinostat hydrochloride monohydrate | 732302-99-7 | 99.6% | 475.97 | 25 MG
Supplier: Medchemexpress LLC 25MGHY14842B
Givinostat hydrochloride monohydrate is a potent HDAC inhibitor, demonstrating IC50 values of 198 nM for HDAC1 and 157 nM for HDAC3. This compound is notable for its ability to penetrate the blood-brain barrier, making it suitable for a range of research applications.
- Potent HDAC inhibitor for HDAC1 and HDAC3
- Penetrates the blood-brain barrier
- Suppresses LPS-induced IL-1β and IL-6 production
- Inhibits JS-1 cell proliferation
- Reduces serum TNFα and IL-1β levels in vivo
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