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Cayman Chemical GlepaglutIdeacetate 10mg
Supplier: Cayman Chemical 4127410 MG
A peptide; agonist of GLP-2R; selectively induces cAMP accumulation in HEK293 cells expressing GLP-2R over those expressing GLP-1R (EC50s = 0.24 and 8.7 nM, respectively, for the human receptors); increases mucosal hyperplasia thickness in the duodenum, jejunum, and ileum, as well as increases small intestinal wet weight and length, in rats at 10 mg/kg per day for 26 weeks; increases small intestinal mass and length, as well as reduces ileal levels of AGP 1 and MPO, in an indomethacin-induced rat model of IBD at 400 nmol/kg twice per day
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