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Apexbio Technology LLC Glibenclamide 10238-21-8 10mM (in 1mL DMSO)
Supplier: Apexbio Technology LLC B12965.1
Glibenclamide (CAS 10238-21-8) is a sulfonylurea-class small molecule widely utilized in biomedical research for its ability to modulate insulin release It acts primarily by binding to ATP-sensitive potassium channels (K ATP channels) in pancreatic beta cells This interaction results in channel closure leading to cellular depolarization calcium ion influx and subsequent insulin secretion Due to its well-characterized mechanism glibenclamide is particularly relevant in diabetes-related research focusing on insulin regulation and beta-cell physiology
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