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Apexbio Technology LLC Gliclazide 21187-98-4 10mM (in 1mL DMSO)
Supplier: Apexbio Technology LLC B21955.1
Gliclazide (CAS 21187-98-4) is an oral hypoglycemic agent classified structurally as a sulfonylurea derivative It exerts its biological effects primarily by targeting pancreatic beta-cell sulfonylurea receptors (SUR1) stimulating insulin secretion through the closure of ATP-dependent potassium channels This channel inhibition induces cellular depolarization facilitating calcium influx and subsequent insulin exocytosis In a research context gliclazide is utilized extensively as a pharmacological tool to study pancreatic beta-cell function insulin secretion dynamics and diabetic pathophysiology
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