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Tocris Bioscience™ GLP-2 (3-33)
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Catalog No. 77251
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77-251 1 mg
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Catalog No. 77-251 Supplier Tocris Bioscience™ Supplier No. 7725/1
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Peptide antagonist of glucagon-like peptide-2 (GLP-2) receptor

GLP-2(3-33) is a peptide antagonist of glucagon-like peptide-2 (GLP-2) receptor. In cells, GLP-2(3-33) is generated by cleaving off the two N-terminal amino acids of GLP-2 with dipeptidylpeptidase IV (DPPIV). In high-fat diet (HFD) fed mice, GLP-2(3-33) treatment results in increased dyslipidemia and hepatic lipid accumulation. Chronic treatment of GLP-2(3-33) in HFD fed mice can cause hyperglycemia, glucose intolerance, high plasma insulin level after glucose load, increased pancreas weight and β-cell expansion.

Specifications

Gene ID (Entrez) 9340
Purity 0.95
CAS 275801-62-2
Content And Storage Store at -20°C
Gene Alias GLP-2 receptor, GLP-2 R, GLP-2-R, glucagon-like peptide 2 receptor
Molecular Weight (g/mol) M.W.-observed: 3557.93
Quantity 1 mg
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