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BioVendor, LLC Glucagon-Like Peptide-2 (GLP-2) Rat ELISA (96 wells)
Supplier: BioVendor, LLC YK140
Glucagon-Like Peptide-2 (GLP-2) Rat ELISA (96 wells). High sensitivity EIA (enzyme immunoassay) for quantitative determination of rat GLP-2 [both GLP-2 (1-33) and GLP-2 (3-33)] in serum or plasma samples. The kit has high specificity to rat GLP-2 and shows no cross reactivity with rat glucagon and rat GLP-1 even in the concentration of 300 pmol/mL. Manufactured by Yanaihara Institute, Japan. SAMPLE REQ: 25 L. ASSAY RANGE 0.137 - 100 ng/mL. SUMMARY: GLP2 is released from the mucosal enteroendocrine L-cells of the intestine. The actions of GLP-2 are transduced by the GLP-2 receptor [GLP-2R], which is localized in the neurons of the enteric nervous system but not in the intestinal epithelium, indicating an indirect mechanism of action. GLP-2 is well known for its trophic role within the intestine and interest in GLP-2 is now reviving based on the approval of the GLP-2R agonist for treatment of short bowel syndrome. Recently, it also seems to be involved in glucose homeostasis.
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