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Bachem (Glu2)-TRH
Supplier: Bachem 4026102.0050
(Glu2)-TRH, Pyr-Glu-Pro-NH2, 85541-78-2, C15H22N4O6, Mr 354.36, 50mg. Fertilization-Promoting Peptide, FPP, pE-E-P-NH2. Fertilization-promoting peptide (FPP), a TRH analog, was previously purified and characterized from both rabbit prostate and human semen. Nanomolar concentrations of this peptide have been shown to enhance capacitation of mouse epididymal spermatozoa with a concomitant increase in fertilizing ability. It was also detected in the thyroid gland. According to a study of Nguyen et al. Pyr-Glu-Pro-NH2 opposes the cholinergic effect of TRH in the mammalian CNS: Co-perfusion with an equivalent of TRH in the rat hippocampus resulted in a significant attenuation of TRH-induced acetylcholine release.
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