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Bachem GLP-1 (9-36) amide (human, bovine, guinea pig, mouse, porcine, rat) Trifluoroacetate

Supplier: Bachem 4027697.0005

GLP-1 (9-36) amide (human, bovine, guinea pig, mouse, porcine, rat) Trifluoroacetate, H-Glu-Gly-Thr-Phe-Thr-Ser-Asp-Val-Ser-Ser-Tyr-Leu-Glu-Gly-Gln-Ala-Ala-Lys-Glu-Phe-Ile-Ala-Trp-Leu-Val-Lys-Gly-Arg-NH2, 161748-29-4, C140H214N36O43, Mr 3089.46, 5mg. Preproglucagon (100-127) amide (human, bovine, guinea pig, mouse, porcine, rat), Glucagon-Like Peptide 1 (9-36) amide (human, bovine, guinea pig, mouse, porcine, rat), Proglucagon (80-107) amide (human, bovine, guinea pig, mouse, porcine, rat). Glucagon-like peptide-1 (GLP-1) is efficiently degraded by the enzyme dipeptidyl peptidase IV (DPP IV), yielding the major metabolite GLP-1 (9-36) amide. GLP-1 (9-36) amide does not affect glucose disposal in mice either in the presence or absence of intact GLP-1 receptors or in the presence or absence of stimulated insulin levels. This suggests that the GLP-1 metabolite is not involved in the regulation of glucose homeostasis.
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