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Bachem GLP-1 (1-37) (human, bovine, guinea pig, mouse, rat), 0.5mg, 87805-34-3, MFCD00131174, Trifluoroacetate salt
Supplier: Bachem 4037542.0500
Glucagon-Like Peptide 1 (GLP-1) is synthesized by post translational processing of proglucagon in the intestine and pancreas and plays an important role in metabolic homeostasis. Among the different molecular forms, such as GLP-1 (7-36) amide and GLP-1 (7-37), the function of GLP-1 (1-37) has been unclear. GLP-1 (1-37) was shown to convert intestinal epithelial cells into insulin-producing cells. These observations turned GLP-1 (1-37) into a new promising therapeutic compound for the treatment of diabetes mellitus. In animal models of dilated cardiomyopathy, hypertensive heart failure, and myocardial infarction, GLP-1 has shown a remarkable cardioprotective activity.
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