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CPC Scientific H-His-Ala-Glu-Gly-Thr-Phe-Thr-Ser-Asp-Val-Ser-Ser-Tyr-Leu-Glu-Gly-Gln-Ala-Ala-Lys-Glu-Phe-Ile-Ala-Trp-Leu-Val-Lys-Gly-Arg-NH2 1MG
Supplier: CPC Scientific GLUC010B
The GLP-1 fragment is isolated from the lower small intestine and is presently regarded to be the most important incretin hormone. It shows a strong insulinotropic effect that is mediated by receptors expressed in the pancreatic beta-cells. It is proposed to be a novel therapeutic strategy for non-insulin-dependent (type 2) diabetes mellitus and associated neuropathy.SEQUENCE: H-His-Ala-Glu-Gly-Thr-Phe-Thr-Ser-Asp-Val-Ser-Ser-Tyr-Leu-Glu-Gly-Gln-Ala-Ala-Lys-Glu-Phe-Ile-Ala-Trp-Leu-Val-Lys-Gly-Arg-NH2ONE-LETTER SEQUENCE: HAEGTFTSDVSSYLEGQAAKEFIAWLVKGR-NH2MOLECULAR FORMULA: C149H226N40O45MOLECULAR WEIGHT: 3297.68STORAGE CONDITIONS: -20 5 CCAS REGISTRY NUMBER: [107444-51-9]SYNONYMS: GLP-1 fragment, Proglucagon (78-107) amide (human, bovine, guinea pig, mouse, rat), Preproglucagon (98-127) amide (human, bovine, guinea pig, mouse, rat), Glucagon-Like Peptide 1 (7-36) amide (human, bovine, guinea pig, mouse, rat)RESEARCH AREA: DiabetesREFERENCES:G. Bell et al., Nature,
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