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Cayman Chemical Glucocorticoid Resistance Inh
Supplier: Cayman Chemical 255531 MG
An inhibitor of glucocorticoid resistance; inhibits growth of CUTTL1 cells when used in combination with dexamethasone (EC50 = 28 µM) and is less effective when used alone (EC50 = 294 µM); preferentially inhibits growth of CUTTL1 cells expressing high levels of the glucocorticoid receptor over cells expressing low levels; upregulates the gene expression and protein levels of the glucocorticoid receptor; restores glucocorticoid sensitivity to dexamethasone-resistant CUTTL1 cells
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