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Cayman Chemical Glucuronidase Inhibitor 1mg
Supplier: Cayman Chemical 412281 MG
An inhibitor of bacterial β-glucuronidase (IC50 = 283 nM for the E. coli enzyme); inhibits wild-type but not Δ360-376 E. coli β-glucuronidase at 100 µM; reduces irinotecan-induced colonic epithelial damage and the number of bloody diarrheal events in a mouse model of chemotherapy-induced intestinal toxicity at 50 mg/kg
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