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Cayman Chemical GlutamInase-IN-3 100mg
SDP

Supplier:  Cayman Chemical 42325100 MG

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A chymase inhibitor (IC50s 4 and 3 nM for the human and hamster enzyme respectively) reduces isoprenaline-induced cardiac fibrosis in hamsters at 1 3 and 10 mg/kg inhibits decreases in left ventricular ejection fraction and increases in left ventricular end-systolic volume decreases in plasma levels of nt-proBNP TGF-B1 and TNF-a as well as the levels of interstitial fibrosis and the cross-sectional area of myocytes in a coronary microembolism-induced canine model of heart failure at 2 and 5 mg/kg per day

Catalog No. 50-294-3507


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